In vitro transdifferentiation of hepatoma cells into functional pancreatic cells
نویسندگان
چکیده
منابع مشابه
In vitro transdifferentiation of hepatoma cells into functional pancreatic cells
We have characterised the transdifferentiation of human HepG2 (hepatoma) cells to pancreatic cells following introduction of an activated version of the pancreatic transcription factor Pdx1 (XlHbox8-VP16). The following questions are addressed: (1) are all types of pancreatic cells produced? (2) is the requirement for expression of the transgene temporary or permanent? (3) are the transdifferen...
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ژورنال
عنوان ژورنال: Mechanisms of Development
سال: 2005
ISSN: 0925-4773
DOI: 10.1016/j.mod.2005.01.001